Does Take onglyza 5 mg tablet lower blood sugar?-healthcare

onglyza 5 mg

onglyza 5 mg tablet

onglyza 5 (saxagliptin) is an oral prescription medicine for adults with type 2 diabetes. Designed to be use alongside diet and exercise, the drug helps to control high blood glucose levels amongst type 2 diabetics.

Onglyza 5 Mg Tablet is a dipeptidyl peptidase-4 inhibitor. It is use for the treatment of type 2 diabetes. It is a type of antidiabetic medication use in case proper diet and exercise alone is not sufficient to control and curb diabetes. Onglyza 5Mg Tablet works by stimulating increase in the insulin secretion and decrease in sugar produce by your body.

How does Onglyza work?

Onglyza is a daily diabetes drug in the class known as gliptins (DPP-4 inhibitors).

These drugs help to control blood glucose levels by increasing the amount of insulin released by the pancreas and decreasing the body’s release of glucagon.

Onglyza is used alone or alongside other oral diabetes medicines.

These may include metformin, thiazolidinedione or a sulfonylurea.


In Treatment of Type 2 diabetes mellitus

Onglyza 5mg Tablet belongs to a group of medicines called DPP-4 inhibitors (or gliptins). It helps increase the amount of insulin your body produces after a meal and to stop your body from releasing too much glucose (sugar) into your blood. This way it lowers the blood glucose levels in your body. It is usually taken once a day and has relatively few common side effects.

Lowering blood glucose levels is an essential part of managing diabetes. Controlling the blood glucose level helps prevent serious complications of diabetes such as kidney damage, blindness, and loss of limbs. Proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed for long-term benefits.

Onglyza 5 mg Tablet 14’s work by blocking the action of DPP-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed. Thus, Onglyza 5 mg Tablet 14’s plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing. Read more: onglyza medicine


Diabetic Foot - Diabetes Mellitus in Feet | Pivotal Motion


Directions for Use

Swallow the tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the day, at least 4 hours apart. Do not chew or crush it.


Store in a cool and dry place away from sunlight

Side Effects of Onglyza 5 mg Tablet 14’s

Most of the side effects of Onglyza 5 mg Tablet 14’s do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Some common side effect of Onglyza 5 mg Tablet 14’s are hypoglycaemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold) and headache. But these would be temporary and may be relieve after some time. However, if you still have discomfort speak with the doctor.

In-Depth Precautions and Warning

Drug Warnings

Increased risk of hypoglycemia (low blood sugar level) can occur when Onglyza 5 mg Tablet 14’s is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Onglyza 5 mg Tablet 14’s. Prolonged intake of Onglyza 5 mg Tablet 14’s may cause acute pancreatitis (swollen pancreas), and critical kidney problem. Severe allergic reactions might occur in some patients taking Onglyza 5 mg Tablet 14’s like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions including Stevens-Johnson syndrome. Safety and efficacy of Onglyza 5 mg Tablet 14’s in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Onglyza 5 mg Tablet 14’s should be closely monitored as severe drug interaction has been observed.

Drug Interactions

Drug-Drug Interaction: Onglyza 5 mg Tablet 14’s interacts with an anti-depressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-HIV drugs (dolutegravir), ethanol, saliva reducing drugs (glycopyrrolate), iodinated X-ray contrast agents, anti-epileptic drugs (topiramate, lamotrigine), heart-related chest medicine (ranolazine).

Other drug interactions can contribute to an increased low blood sugar including sex hormones (androgens), anti-oxidant (alpha-lipoic acid), painkillers (aspirin), anti TB drugs (prothionamide), growth hormones (pegvisomant), and other antidiabetic medicines.

Drug-Food Interaction: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic Acidosis. So, avoid intake of alcoholic beverages with Onglyza 5 mg Tablet 14’s.

Drug-Disease Interaction: Onglyza 5 mg Tablet 14’s should be use with caution in patients with a history of pancreatitis/pancreatic disease and renal dysfunction.

Diet & Lifestyle Advise

  • Invest at least 150 min of your week in moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise every week.
  • Losing weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replacing refined carbohydrates containing foods with whole grain foods and increase intake of fruits and veggies and other fibre enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in the food like chips, crisps, pastries, biscuits and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Avoid taking too much stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes or meditation or yoga.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
  • Keep your blood pressure as normal (140/90) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.


Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Onglyza 5mg Tablet may be take with or without food, but it is better to take it at a fixed time.


Onglyza 5mg Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

type diabetes

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

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